5VDH

Crystal Structure of Human Glycine Receptor alpha-3 Bound to AM-3607, Glycine, and Ivermectin

Summary for 5VDH

• Entry DOI: 10.2210/pdb5vdh/pdb
• Related: 5VDI
• Descriptor: Glycine receptor subunit alpha-3, (3S,3aS,9bS)-2-[(2H-1,3-benzodioxol-5-yl)sulfonyl]-3,5-dimethyl-1,2,3,3a,5,9b-hexahydro-4H-pyrrolo[3,4-c][1,6]naphthyridin-4-one, GLYCINE, ... (8 entities in total)
• Functional Keywords: ligand-gated ion channel, neurotransmitter receptor, membrane protein, cys-loop receptor, transport protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 216628.70

Authors

Shaffer, P.L.,Huang, X.,Chen, H. (deposition date: 2017-04-03, release date: 2017-05-24, Last modification date: 2023-10-04)

• Primary citation: Huang, X.,Chen, H.,Shaffer, P.L.; Crystal Structures of Human GlyR alpha 3 Bound to Ivermectin.; Structure, 25:945-950.e2, 2017; PubMed: 28479061; DOI: 10.1016/j.str.2017.04.007

Experimental method

X-RAY DIFFRACTION (2.85 Å)