5VDC
Crystal structure of the human DPF2 tandem PHD finger domain
Summary for 5VDC
Entry DOI | 10.2210/pdb5vdc/pdb |
Descriptor | Zinc finger protein ubi-d4, ZINC ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | histone reader, tandem phd finger, aml, myeloid differentiation, gene regulation |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 14695.93 |
Authors | Huber, F.M.,Davenport, A.M.,Hoelz, A. (deposition date: 2017-04-01, release date: 2017-05-24, Last modification date: 2024-03-06) |
Primary citation | Huber, F.M.,Greenblatt, S.M.,Davenport, A.M.,Martinez, C.,Xu, Y.,Vu, L.P.,Nimer, S.D.,Hoelz, A. Histone-binding of DPF2 mediates its repressive role in myeloid differentiation. Proc. Natl. Acad. Sci. U.S.A., 114:6016-6021, 2017 Cited by PubMed: 28533407DOI: 10.1073/pnas.1700328114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report