5VCS

Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with Bound Acceptor

5VCS の概要

• エントリーDOI: 10.2210/pdb5vcs/pdb
• 関連するPDBエントリー: 5VCM 5VCR
• 分子名称: Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: glycosyltransferase, mgat2, complex n-gly, branched acceptor, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 99300.81

構造登録者

Sanders, J.H.,Kadirvelraj, R.,Wood, Z.A. (登録日: 2017-03-31, 公開日: 2018-04-11, 最終更新日: 2023-10-04)

• 主引用文献: Kadirvelraj, R.,Yang, J.Y.,Sanders, J.H.,Liu, L.,Ramiah, A.,Prabhakar, P.K.,Boons, G.J.,Wood, Z.A.,Moremen, K.W.; HumanN-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite.; Proc. Natl. Acad. Sci. U.S.A., 115:4637-4642, 2018; PubMed: 29666272; DOI: 10.1073/pnas.1716988115

実験手法

X-RAY DIFFRACTION (2.799 Å)