5VAA

Crystal structure of mouse IgG2a Fc T370K mutant

5VAA の概要

• エントリーDOI: 10.2210/pdb5vaa/pdb
• 分子名称: Ig gamma-2A chain C region, A allele, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: fc, immunoglobulin fold, immune system
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55146.16

構造登録者

Armstrong, A.A.,Gilliland, G.L. (登録日: 2017-03-24, 公開日: 2017-06-07, 最終更新日: 2020-07-29)

• 主引用文献: Labrijn, A.F.,Meesters, J.I.,Bunce, M.,Armstrong, A.A.,Somani, S.,Nesspor, T.C.,Chiu, M.L.,Altintas, I.,Verploegen, S.,Schuurman, J.,Parren, P.W.H.I.; Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models.; Sci Rep, 7:2476-2476, 2017; PubMed: 28559564; DOI: 10.1038/s41598-017-02823-9

実験手法

X-RAY DIFFRACTION (1.55 Å)