5V6M

Crystal Structure of Rabbit Anti-HIV-1 gp120 V3 Fab 10A3 in complex with V3 peptide ConB

5V6M の概要

• エントリーDOI: 10.2210/pdb5v6m/pdb
• 関連するPDBエントリー: 5V5L
• 分子名称: Light chain of Fab fragment of rabbit anti-HIV1 gp120 V3 mAb 10A3, Heavy chain of Fab fragment of rabbit anti-HIV1 gp120 V3 mAb 10A3, Envelope glycoprotein gp120 V3 peptide of Con B sequence, ... (5 entities in total)
• 機能のキーワード: hiv, gp120, v3, antibody, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Oryctolagus cuniculus (rabbit); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 47401.87

構造登録者

Pan, R.,Kong, X.-P. (登録日: 2017-03-17, 公開日: 2018-01-17, 最終更新日: 2019-12-11)

• 主引用文献: Pan, R.,Qin, Y.,Banasik, M.,Lees, W.,Shepherd, A.J.,Cho, M.W.,Kong, X.P.; Increased epitope complexity correlated with antibody affinity maturation and a novel binding mode revealed by structures of rabbit antibodies against the third variable loop (V3) of HIV-1 gp120.; J. Virol., 2018; PubMed: 29343576; DOI: 10.1128/JVI.01894-17

実験手法

X-RAY DIFFRACTION (1.9 Å)