5V5C
VQIINK, Structure of the amyloid-spine from microtubule associated protein tau Repeat 2
Summary for 5V5C
| Entry DOI | 10.2210/pdb5v5c/pdb |
| Related | 5V5B |
| EMDB information | 8634 8635 |
| Descriptor | Microtubule-associated protein tau (1 entity in total) |
| Functional Keywords | amyloid, tau, alzheimer's disease, tauopathy, mapt, structural protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 714.87 |
| Authors | Seidler, P.M.,Sawaya, M.R.,Rodriguez, J.A.,Eisenberg, D.S.,Cascio, D.,Boyer, D.R. (deposition date: 2017-03-14, release date: 2018-02-07, Last modification date: 2024-03-13) |
| Primary citation | Seidler, P.M.,Boyer, D.R.,Rodriguez, J.A.,Sawaya, M.R.,Cascio, D.,Murray, K.,Gonen, T.,Eisenberg, D.S. Structure-based inhibitors of tau aggregation. Nat Chem, 10:170-176, 2018 Cited by PubMed: 29359764DOI: 10.1038/nchem.2889 PDB entries with the same primary citation |
| Experimental method | ELECTRON CRYSTALLOGRAPHY (1.25 Å) |
Structure validation
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