5V4Q

Crystal Structure of human GGT1 in complex with DON

Summary for 5V4Q

• Entry DOI: 10.2210/pdb5v4q/pdb
• Descriptor: Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: ntn-hydrolase family, glycoprotein, n- glycosylation, cell surface, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 60132.42

Authors

Terzyan, S.,Hanigan, M. (deposition date: 2017-03-10, release date: 2017-04-19, Last modification date: 2023-10-04)

• Primary citation: Terzyan, S.S.,Cook, P.F.,Heroux, A.,Hanigan, M.H.; Structure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation.; Protein Sci., 26:1196-1205, 2017; PubMed: 28378915; DOI: 10.1002/pro.3172

Experimental method

X-RAY DIFFRACTION (2.2 Å)