5V3F
Co-crystal structure of the fluorogenic RNA Mango
Summary for 5V3F
Entry DOI | 10.2210/pdb5v3f/pdb |
Descriptor | RNA (31-MER), POTASSIUM ION, 4-{[(2S)-3-{2,16-dioxo-20-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-2,3-dihydro-1,3-benzothiazol-2-yl]methyl}-1-methylquinolin-1-ium, ... (5 entities in total) |
Functional Keywords | quadruplex fluorescent rna, rna |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 22428.93 |
Authors | Trachman, R.J.,Ferre-D'Amare, A.R. (deposition date: 2017-03-07, release date: 2017-05-24, Last modification date: 2024-03-06) |
Primary citation | Trachman, R.J.,Demeshkina, N.A.,Lau, M.W.L.,Panchapakesan, S.S.S.,Jeng, S.C.Y.,Unrau, P.J.,Ferre-D'Amare, A.R. Structural basis for high-affinity fluorophore binding and activation by RNA Mango. Nat. Chem. Biol., 13:807-813, 2017 Cited by PubMed: 28553947DOI: 10.1038/nchembio.2392 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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