5V2H
RNA octamer containing glycol nucleic acid, SgnT
Summary for 5V2H
Entry DOI | 10.2210/pdb5v2h/pdb |
Descriptor | RNA (5'-R(*(CBV)P*GP*AP*AP*(ZTH)P*UP*CP*G)-3'), COBALT HEXAMMINE(III), MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | rna, glycol nucleic acid |
Biological source | synthetic construct |
Total number of polymer chains | 4 |
Total formula weight | 10431.21 |
Authors | Harp, J.M.,Egli, M. (deposition date: 2017-03-04, release date: 2017-06-14, Last modification date: 2024-05-22) |
Primary citation | Schlegel, M.K.,Foster, D.J.,Kel'in, A.V.,Zlatev, I.,Bisbe, A.,Jayaraman, M.,Lackey, J.G.,Rajeev, K.G.,Charisse, K.,Harp, J.,Pallan, P.S.,Maier, M.A.,Egli, M.,Manoharan, M. Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. J. Am. Chem. Soc., 139:8537-8546, 2017 Cited by PubMed: 28570818DOI: 10.1021/jacs.7b02694 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.08001306231 Å) |
Structure validation
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