5V1L
Structure of S-GNA dodecamer
Summary for 5V1L
Entry DOI | 10.2210/pdb5v1l/pdb |
Descriptor | RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*(ZTH)P*AP*GP*CP*G)-3'), STRONTIUM ION, SPERMINE, ... (4 entities in total) |
Functional Keywords | glycol nucleic acid, gna, rna, rna x-ray structure, nuclease stability, modified rna |
Biological source | synthetic construct |
Total number of polymer chains | 4 |
Total formula weight | 16132.70 |
Authors | Pallan, P.S.,Egli, M. (deposition date: 2017-03-02, release date: 2017-06-14, Last modification date: 2024-05-22) |
Primary citation | Schlegel, M.K.,Foster, D.J.,Kel'in, A.V.,Zlatev, I.,Bisbe, A.,Jayaraman, M.,Lackey, J.G.,Rajeev, K.G.,Charisse, K.,Harp, J.,Pallan, P.S.,Maier, M.A.,Egli, M.,Manoharan, M. Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. J. Am. Chem. Soc., 139:8537-8546, 2017 Cited by PubMed: 28570818DOI: 10.1021/jacs.7b02694 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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