5V0W

Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001088

5V0W の概要

• エントリーDOI: 10.2210/pdb5v0w/pdb
• 関連するPDBエントリー: 5v0x
• 分子名称: Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA, 1-[5-[3,4-bis(fluoranyl)-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-1-methyl-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, ... (6 entities in total)
• 機能のキーワード: ssgcid, glycylpeptide n-tetradecanoyltransferase, n-myristoyltransferase, nmt, plasmodium vival, salvador i, structural genomics, seattle structural genomics center for infectious disease, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Plasmodium vivax
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 147281.04

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2017-02-28, 公開日: 2018-03-07, 最終更新日: 2023-10-04)

• 主引用文献: Mayclin, S.J.,Abendroth, J.,Lorimer, D.D.,Edwards, T.E.; Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001088; to be published,

実験手法

X-RAY DIFFRACTION (1.8 Å)