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5V0A

Crystal structure of human exonuclease 1 Exo1 (D225A) in complex with 5' recessed-end DNA (rVIII)

Summary for 5V0A
Entry DOI10.2210/pdb5v0a/pdb
Related5UZV 5V04 5V05 5V06 5V07 5V08 5V09 5V0B 5V0C 5V0D 5V0E
DescriptorExonuclease 1, DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), ... (7 entities in total)
Functional Keywordsexonuclease, endonuclease, hydrolase-dna complex, hydrolase/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight47677.98
Authors
Shi, Y.,Beese, L.S. (deposition date: 2017-02-28, release date: 2017-05-24, Last modification date: 2023-10-04)
Primary citationShi, Y.,Hellinga, H.W.,Beese, L.S.
Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I.
Proc. Natl. Acad. Sci. U.S.A., 114:6010-6015, 2017
Cited by
PubMed: 28533382
DOI: 10.1073/pnas.1704845114
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.38 Å)
Structure validation

217157

数据于2024-03-13公开中

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