5UXE

Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P178

Summary for 5UXE

• Entry DOI: 10.2210/pdb5uxe/pdb
• Related: 4Q32 4Q33 5UWX
• Descriptor: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, N-[4-chloro-3-(alpha-D-ribofuranosyloxy)phenyl]-N'-{2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}urea, ... (8 entities in total)
• Functional Keywords: tim barrel, impdh, csgid, dehydrogenase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Clostridium perfringens; More
• Total number of polymer chains: 4
• Total formula weight: 157561.42

Authors

Maltseva, N.,Kim, Y.,Mulligan, R.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.R.,Hedstrom, L.,Joachimiak, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-02-22, release date: 2017-03-08, Last modification date: 2023-10-04)

• Primary citation: Maltseva, N.,Kim, Y.,Mulligan, R.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.R.,Hedstrom, L.,Joachimiak, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P178; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)