5UUF
Bacillus cereus DNA glycosylase AlkD bound to a yatakemycin-adenine nucleobase adduct and DNA containing an abasic site (12-mer product complex)
Summary for 5UUF
Entry DOI | 10.2210/pdb5uuf/pdb |
Related | 5UUG 5UUH 5UUJ |
Descriptor | DNA-7-methylguanine glycosylase, DNA (5'-D(*CP*CP*CP*CP*AP*(ORP)P*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*GP*CP*TP*TP*TP*GP*GP*GP*G)-3'), ... (5 entities in total) |
Functional Keywords | dna glycosylase, protein-dna complex, alkylpurine, bulky lesion, hydrolase-dna-antibiotic complex, hydrolase/dna/antibiotic |
Biological source | Bacillus cereus More |
Total number of polymer chains | 3 |
Total formula weight | 36603.53 |
Authors | Mullins, E.A.,Eichman, B.F. (deposition date: 2017-02-16, release date: 2017-07-19, Last modification date: 2023-10-04) |
Primary citation | Mullins, E.A.,Shi, R.,Eichman, B.F. Toxicity and repair of DNA adducts produced by the natural product yatakemycin. Nat. Chem. Biol., 13:1002-1008, 2017 Cited by PubMed: 28759018DOI: 10.1038/nchembio.2439 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.612 Å) |
Structure validation
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