5UTJ

Crystal Structure of TGT in complex with 2,6-dioxy-8-azapurine, 2,6-dioxy-8-azapurine, 2,6-dioxy-8-azapurine

Summary for 5UTJ

• Entry DOI: 10.2210/pdb5utj/pdb
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• Functional Keywords: tgt, trna, guanine exchange enzyme, transglycosylase, fragments, transferase
• Biological source: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
• Total number of polymer chains: 1
• Total formula weight: 42272.36

Authors

Hassaan, E.,Heine, A.,Klebe, G. (deposition date: 2017-02-15, release date: 2018-03-07, Last modification date: 2024-01-17)

• Primary citation: Hassaan, E.,Eriksson, P.O.,Geschwindner, S.,Heine, A.,Klebe, G.; Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies.; Chemmedchem, 15:324-337, 2020; PubMed: 31808981; DOI: 10.1002/cmdc.201900604

Experimental method

X-RAY DIFFRACTION (1.549 Å)