5UQF

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with IMP and the inhibitor P225

5UQF の概要

• エントリーDOI: 10.2210/pdb5uqf/pdb
• 関連するPDBエントリー: 4MZ1 4MZ8 4R7J 5UPU 5UPV 5UPX 5UPY 5UQG 5UQH 5URQ 5URR 5URS
• 分子名称: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, {2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenoxy}acetic acid, ... (9 entities in total)
• 機能のキーワード: impdh, tim barrel, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Campylobacter jejuni subsp. jejuni; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 134533.12

構造登録者

Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2017-02-08, 公開日: 2017-03-01, 最終更新日: 2023-10-04)

• 主引用文献: Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with IMP and the inhibitor P225; To Be Published,

実験手法

X-RAY DIFFRACTION (2.73 Å)