5UPG
Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PF-5081090
Summary for 5UPG
Entry DOI | 10.2210/pdb5upg/pdb |
Descriptor | UDP-3-O-acyl-N-acetylglucosamine deacetylase, (2R)-4-[4-(2-fluoro-4-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, ZINC ION, ... (6 entities in total) |
Functional Keywords | ssgcid, lpxc, udp-3-o-acyl-n-acetylglucosamine deacetylase, pf-5081090, lipid a biosynthesis, structural genomics, seattle structural genomics center for infectious disease, hydrolase |
Biological source | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Total number of polymer chains | 1 |
Total formula weight | 34925.67 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2017-02-02, release date: 2017-03-29, Last modification date: 2023-10-04) |
Primary citation | Phan, J.N.,Delker, S.L.,Lorimer, D.D.,Edwards, T.E. Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PF-5081090 to be published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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