5UOW
Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, MK-801 and a GluN2B-specific Fab, at pH 6.5
Summary for 5UOW
Entry DOI | 10.2210/pdb5uow/pdb |
Related | 5UP2 |
EMDB information | 8579 8581 |
Descriptor | N-methyl-D-aspartate receptor subunit NR1-8a, N-methyl-D-aspartate receptor subunit NR2A, Ionotropic glutamate receptor subunit NR2B, ... (7 entities in total) |
Functional Keywords | membrane protein |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 6 |
Total formula weight | 412061.18 |
Authors | Lu, W.,Du, J.,Goehring, A.,Gouaux, E. (deposition date: 2017-02-01, release date: 2017-03-22, Last modification date: 2020-07-29) |
Primary citation | Lu, W.,Du, J.,Goehring, A.,Gouaux, E. Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation. Science, 355:-, 2017 Cited by PubMed: 28232581DOI: 10.1126/science.aal3729 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.5 Å) |
Structure validation
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