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5UML

CRYSTAL STRUCTURE OF HUMAN MDMX IN COMPLEX WITH 12-MER PEPTIDE INHIBITOR M3

Summary for 5UML
Entry DOI10.2210/pdb5uml/pdb
Related5UMM
DescriptorProtein Mdm4, PEPTIDE INHIBITOR M3 (2 entities in total)
Functional Keywordsoncoprotein, cell cycle, antitumor protein-inhibitor complex, antitumor protein/inhibitor
Biological sourceHomo sapiens (Human)
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Total number of polymer chains8
Total formula weight44472.35
Authors
Pazgier, M.,Gohain, N.,Tolbert, W.D. (deposition date: 2017-01-27, release date: 2018-01-31, Last modification date: 2023-10-04)
Primary citationPazgier, M.,Gohain, N.,Tolbert, W.D.
Design of ultrahigh-affinity and dual-specificity peptide antagonists of MDM2 and MDMX for p53 activation
To Be Published,
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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