5UJJ
Crystal structure of human H130R tryptophanyl-tRNA synthetase in complex with TrpAMP
Summary for 5UJJ
Entry DOI | 10.2210/pdb5ujj/pdb |
Related | 5UJI |
Descriptor | Tryptophan--tRNA ligase, cytoplasmic, TRYPTOPHANYL-5'AMP, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | rossmann-fold catalytic domain, anti-codon binding domain, h130r mutation, ligase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 110693.78 |
Authors | Xu, X.,Yang, X.-L. (deposition date: 2017-01-18, release date: 2018-01-17, Last modification date: 2023-10-04) |
Primary citation | Xu, X.,Zhou, H.,Zhou, Q.,Hong, F.,Vo, M.N.,Niu, W.,Wang, Z.,Xiong, X.,Nakamura, K.,Wakasugi, K.,Schimmel, P.,Yang, X.L. An alternative conformation of human TrpRS suggests a role of zinc in activating non-enzymatic function. RNA Biol, 15:649-658, 2018 Cited by PubMed: 28910573DOI: 10.1080/15476286.2017.1377868 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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