5UJJ

Crystal structure of human H130R tryptophanyl-tRNA synthetase in complex with TrpAMP

Summary for 5UJJ

• Entry DOI: 10.2210/pdb5ujj/pdb
• Related: 5UJI
• Descriptor: Tryptophan--tRNA ligase, cytoplasmic, TRYPTOPHANYL-5'AMP, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: rossmann-fold catalytic domain, anti-codon binding domain, h130r mutation, ligase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 110693.78

Authors

Xu, X.,Yang, X.-L. (deposition date: 2017-01-18, release date: 2018-01-17, Last modification date: 2023-10-04)

• Primary citation: Xu, X.,Zhou, H.,Zhou, Q.,Hong, F.,Vo, M.N.,Niu, W.,Wang, Z.,Xiong, X.,Nakamura, K.,Wakasugi, K.,Schimmel, P.,Yang, X.L.; An alternative conformation of human TrpRS suggests a role of zinc in activating non-enzymatic function.; RNA Biol, 15:649-658, 2018; PubMed: 28910573; DOI: 10.1080/15476286.2017.1377868

Experimental method

X-RAY DIFFRACTION (2.1 Å)