5UGV

DapB from Mycobacterium tuberculosis

5UGV の概要

• エントリーDOI: 10.2210/pdb5ugv/pdb
• 分子名称: 4-hydroxy-tetrahydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: lysine biosynthesis, dapb, oxidoreductase
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
• 細胞内の位置: Cytoplasm : A5U6C6
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58769.83

構造登録者

Pote, S.P.,Mank, N.,Chruszcz, M. (登録日: 2017-01-10, 公開日: 2018-01-17, 最終更新日: 2023-10-04)

• 主引用文献: Pote, S.,Kachhap, S.,Mank, N.J.,Daneshian, L.,Klapper, V.,Pye, S.,Arnette, A.K.,Shimizu, L.S.,Borowski, T.,Chruszcz, M.; Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus.; Biochim Biophys Acta Gen Subj, 1865:129750-129750, 2021; PubMed: 32980502; DOI: 10.1016/j.bbagen.2020.129750

実験手法

X-RAY DIFFRACTION (2.25 Å)