5UDA

Crystal structure of CYP2B6 (Y226H/K262R) in complex with a monoterpene bornane

Summary for 5UDA

Entry DOI	10.2210/pdb5uda/pdb
Related	5UEC
Descriptor	Cytochrome P450 2B6, PROTOPORPHYRIN IX CONTAINING FE, CAMPHANE, ... (5 entities in total)
Functional Keywords	oxidoreductase, cytochrome p450, cyp2b6
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	113768.92
Authors	Shah, M.B.,Halpert, J.R. (deposition date: 2016-12-24, release date: 2017-04-12, Last modification date: 2023-10-04)
Primary citation	Shah, M.B.,Liu, J.,Zhang, Q.,Stout, C.D.,Halpert, J.R. Halogen-pi Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity. ACS Chem. Biol., 12:1204-1210, 2017 Cited by PubMed: 28368100 DOI: 10.1021/acschembio.7b00056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation