5UC3
Structure of the dominant negative mutant Glucocorticoid Receptor alpha (L733K/N734P) complexed with RU-486
Summary for 5UC3
Entry DOI | 10.2210/pdb5uc3/pdb |
Descriptor | Glucocorticoid receptor, 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total) |
Functional Keywords | nuclear receptor, hormone receptor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 61728.21 |
Authors | Min, J.,Cidlowski, J.A.,Pedersen, L.C. (deposition date: 2016-12-21, release date: 2017-12-27, Last modification date: 2023-10-04) |
Primary citation | Min, J.,Pedersen, L.C. Nuclear receptor To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.009 Å) |
Structure validation
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