5UAO
Crystal structure of MibH, a lathipeptide tryptophan 5-halogenase
Summary for 5UAO
Entry DOI | 10.2210/pdb5uao/pdb |
Descriptor | Tryptophane-5-halogenase, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | halogenase, lanthipeptide, tryptophan, nai-107, oxidoreductase |
Biological source | Microbispora sp. ATCC PTA-5024 |
Total number of polymer chains | 4 |
Total formula weight | 238593.90 |
Authors | Cogan, D.P.,Nair, S.K. (deposition date: 2016-12-19, release date: 2017-01-25, Last modification date: 2023-10-04) |
Primary citation | Ortega, M.A.,Cogan, D.P.,Mukherjee, S.,Garg, N.,Li, B.,Thibodeaux, G.N.,Maffioli, S.I.,Donadio, S.,Sosio, M.,Escano, J.,Smith, L.,Nair, S.K.,van der Donk, W.A. Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis. ACS Chem. Biol., 12:548-557, 2017 Cited by PubMed: 28032983DOI: 10.1021/acschembio.6b01031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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