5U9H

DNA polymerase beta product complex with inserted Sp-isomer of dCTP-alpha-S

Summary for 5U9H

DescriptorDNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(C7R))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... (8 entities in total)
Functional Keywordstransferase, lyase, dna, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
More
Cellular locationNucleus P06746
Total number of polymer chains4
Total molecular weight48433.83
Authors
Freudenthal, B.D.,Wilson, S.H.,Beard, W.A. (deposition date: 2016-12-16, release date: 2017-02-08, Last modification date: 2017-09-27)
Primary citation
Perera, L.,Freudenthal, B.D.,Beard, W.A.,Pedersen, L.G.,Wilson, S.H.
Revealing the role of the product metal in DNA polymerase beta catalysis.
Nucleic Acids Res., 45:2736-2745, 2017
PubMed: 28108654 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gkw1363
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.85 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.237200.4%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution