5U66

Modified single helix from the B-domain of protein A bound to IgG1 Fc

5U66 の概要

• エントリーDOI: 10.2210/pdb5u66/pdb
• 関連するBIRD辞書のPRD_ID: PRD_002261
• 分子名称: STAPLED PEPTIDE FROM DOMAIN B OF PROTEIN A, IgG1 fc derived from CD4-fc fusion, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: igg1 fc, staple peptide, protein a, b-domain, immune system-inhibitor complex, immune system/inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26896.14

構造登録者

Ultsch, M.H.,Eigenbrot, C. (登録日: 2016-12-07, 公開日: 2017-05-24, 最終更新日: 2023-11-15)

• 主引用文献: Ultsch, M.,Braisted, A.,Maun, H.R.,Eigenbrot, C.; 3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix.; Protein Eng. Des. Sel., 30:619-625, 2017; PubMed: 28475752; DOI: 10.1093/protein/gzx029

実験手法

X-RAY DIFFRACTION (1.7 Å)