5U4I

Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome

これは巨大構造です。

> 概要

5U4I の概要

関連するPDBエントリー5U4J
EMDBエントリーEMD-8506 EMD-8505
分子名称23S rRNA, 5S rRNA, 50S ribosomal protein L2, ... (58 entities in total)
機能のキーワードribosome, arfa, rf2, nonstop translation
由来する生物種Escherichia coli (strain K12)
詳細
細胞内の位置Cytoplasm P07012
ポリマー鎖数57
分子量合計2249304.24
構造登録者
Zeng, F.,Chen, Y.,Remis, J.,Shekhar, M.,Phillips, J.C.,Tajkhorshid, E.,Jin, H. (登録日: 2016-12-04, 公開日: 2017-01-11, 最終更新日: 2017-09-27)
主引用文献
Zeng, F.,Chen, Y.,Remis, J.,Shekhar, M.,Phillips, J.C.,Tajkhorshid, E.,Jin, H.
Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541:554-557, 2017
PubMed: 28077875 (主引用文献が同じPDBエントリー)
DOI: 10.1038/nature21053
MImport into Mendeley
実験手法
ELECTRON MICROSCOPY
?

構造検証レポート

ClashscoreRamachandran outliersSidechain outliersRNA backbone90.8%6.9%0.41MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
検証レポート(詳細版)をダウンロード

他の静止画像(非対称単位)

Molmil generated image of 5u4i
回転なし
Molmil generated image of 5u4i
x軸(左右方向)周りに90°回転
Molmil generated image of 5u4i
y軸(上下方向)周りに90°回転

> 構造情報

エンティティ

鎖名説明種類鎖長分子量分子数データベース名(アクセス番号)由来する生物種エンティティの一般名
A23S rRNApolymer2904941761.61
GenBank (V00331.1)
Escherichia coli
B5S rRNApolymer11838177.81
GenBank (CP016018.1)
Escherichia coli
C50S ribosomal protein L2polymer27329923.61
UniProt (P60422)
Pfam (PF00181)
Pfam (PF03947)
Escherichia coli (strain K12)
D50S ribosomal protein L3polymer20922277.51
UniProt (P60438)
Pfam (PF00297)
Escherichia coli (strain K12)
E50S ribosomal protein L4polymer20122121.61
UniProt (P60723)
Pfam (PF00573)
Escherichia coli (strain K12)
F50S ribosomal protein L5polymer17920333.61
UniProt (P62399)
Pfam (PF00281)
Pfam (PF00673)
Escherichia coli (strain K12)
G50S ribosomal protein L6polymer17718932.81
UniProt (P0AG55)
Pfam (PF00347)
Escherichia coli (strain K12)
H50S ribosomal protein L9polymer14915789.01
UniProt (P0A7R1)
Pfam (PF01281)
Pfam (PF03948)
Escherichia coli (strain K12)
J50S ribosomal protein L11polymer14214894.41
UniProt (P0A7J7)
Pfam (PF00298)
Pfam (PF03946)
Escherichia coli (strain K12)
K50S ribosomal protein L13polymer14216050.61
UniProt (P0AA10)
Pfam (PF00572)
Escherichia coli (strain K12)
L50S ribosomal protein L14polymer12313565.11
UniProt (P0ADY3)
Pfam (PF00238)
Escherichia coli (strain K12)
M50S ribosomal protein L15polymer14415008.51
UniProt (P02413)
Pfam (PF00828)
Escherichia coli (strain K12)
N50S ribosomal protein L16polymer13615312.31
UniProt (P0ADY7)
Pfam (PF00252)
Escherichia coli (strain K12)
O50S ribosomal protein L17polymer12714393.71
UniProt (P0AG44)
Pfam (PF01196)
Escherichia coli (strain K12)
P50S ribosomal protein L18polymer11712794.71
UniProt (P0C018)
Pfam (PF00861)
Escherichia coli (strain K12)
Q50S ribosomal protein L19polymer11513159.31
UniProt (P0A7K6)
Pfam (PF01245)
Escherichia coli (strain K12)
R50S ribosomal protein L20polymer11813528.01
UniProt (P0A7L3)
Pfam (PF00453)
Escherichia coli (strain K12)
S50S ribosomal protein L21polymer10311586.41
UniProt (P0AG48)
Pfam (PF00829)
Escherichia coli (strain K12)
T50S ribosomal protein L22polymer11012253.41
UniProt (P61175)
Pfam (PF00237)
Escherichia coli (strain K12)
U50S ribosomal protein L23polymer10011222.21
UniProt (P0ADZ0)
Pfam (PF00276)
Escherichia coli (strain K12)
V50S ribosomal protein L24polymer10411339.31
UniProt (P60624)
Pfam (PF00467)
Pfam (PF17136)
Escherichia coli (strain K12)
W50S ribosomal protein L25polymer9410713.51
UniProt (P68919)
Pfam (PF01386)
Escherichia coli (strain K12)
X50S ribosomal protein L27polymer859146.51
UniProt (P0A7L8)
Pfam (PF01016)
Escherichia coli (strain K12)
Y50S ribosomal protein L28polymer789027.61
UniProt (P0A7M2)
Pfam (PF00830)
Escherichia coli (strain K12)
Z50S ribosomal protein L29polymer637286.51
UniProt (P0A7M6)
Pfam (PF00831)
Escherichia coli (strain K12)
050S ribosomal protein L30polymer596554.81
UniProt (P0AG51)
Pfam (PF00327)
Escherichia coli
150S ribosomal protein L32polymer576463.41
UniProt (P0A7N4)
Pfam (PF01783)
Escherichia coli
250S ribosomal protein L33polymer556388.61
UniProt (P0A7N9)
Pfam (PF00471)
Escherichia coli
350S ribosomal protein L34polymer465397.51
UniProt (P0A7P5)
Pfam (PF00468)
Escherichia coli
450S ribosomal protein L35polymer657313.01
UniProt (P0A7Q1)
Pfam (PF01632)
Escherichia coliRibosomal protein A
550S ribosomal protein L36polymer384377.41
UniProt (P0A7Q6)
Pfam (PF00444)
Escherichia coliRibosomal protein B
a16S rRNApolymer1533497044.81
GenBank (CP011320.1)
Escherichia coli
b30S ribosomal protein S2polymer24126781.71
UniProt (P0A7V0)
Pfam (PF00318)
Escherichia coli
c30S ribosomal protein S3polymer23326031.31
UniProt (P0A7V3)
Pfam (PF00189)
Pfam (PF07650)
Escherichia coli
d30S ribosomal protein S4polymer20623514.21
UniProt (P0A7V8)
Pfam (PF00163)
Pfam (PF01479)
Escherichia coli
e30S ribosomal protein S5polymer16717629.41
UniProt (P0A7W1)
Pfam (PF00333)
Pfam (PF03719)
Escherichia coli
f30S ribosomal protein S6polymer13515727.51
UniProt (P02358)
Pfam (PF01250)
Escherichia coli (strain K12)
g30S ribosomal protein S7polymer17920055.21
UniProt (P02359)
Pfam (PF00177)
Escherichia coli (strain K12)
h30S ribosomal protein S8polymer12914015.41
UniProt (P0A7W7)
Pfam (PF00410)
Escherichia coli
i30S ribosomal protein S9polymer13014886.31
UniProt (P0A7X3)
Pfam (PF00380)
Escherichia coli
j30S ribosomal protein S10polymer10311755.61
UniProt (P0A7R5)
Pfam (PF00338)
Escherichia coli
k30S ribosomal protein S11polymer11712487.21
UniProt (P0A7R9)
Pfam (PF00411)
Escherichia coli
l30S ribosomal protein S12polymer12313637.01
UniProt (P0A7S3)
Pfam (PF00164)
Escherichia coli
m30S ribosomal protein S13polymer11813128.51
UniProt (P0A7S9)
Pfam (PF00416)
Escherichia coli
n30S ribosomal protein S14polymer10011475.41
UniProt (P0AG59)
Pfam (PF00253)
Escherichia coli
o30S ribosomal protein S15polymer8810159.61
UniProt (P0ADZ4)
Pfam (PF00312)
Escherichia coli
p30S ribosomal protein S16polymer829207.61
UniProt (P0A7T3)
Pfam (PF00886)
Escherichia coli
q30S ribosomal protein S17polymer849724.51
UniProt (P0AG63)
Pfam (PF00366)
Escherichia coli
r30S ribosomal protein S18polymer759063.51
UniProt (P0A7T7)
Pfam (PF01084)
Escherichia coli
s30S ribosomal protein S19polymer829349.91
UniProt (P0A7U3)
Pfam (PF00203)
Escherichia coli
t30S ribosomal protein S20polymer869577.31
UniProt (P0A7U7)
Pfam (PF01649)
Escherichia coli
u30S ribosomal protein S21polymer718524.01
UniProt (P68679)
Pfam (PF01165)
Escherichia coli
vPeptide chain release factor 2polymer38343313.91
UniProt (P07012)
Pfam (PF00472)
Pfam (PF03462)
Escherichia coli (strain K12)RF-2
wAlternative ribosome-rescue factor Apolymer576513.41
UniProt (P36675)
Pfam (PF03889)
Escherichia coli (strain K12)
x, yP-site or E-site fMet-tRNA(fMet)polymer7724802.82
GenBank (CP012693.1)
Escherichia coli
zmRNApolymer185922.61
Escherichia coli
MAGNESIUM IONnon-polymer24.3124
ZINC IONnon-polymer65.41

配列ビューア

非対称単位の内容

ポリマー鎖の数57
分子量合計2246225.0
非ポリマー*分子数125
分子量合計3079.2
全て*分子量合計2249304.2
*水分子は含んでいません

> 実験情報

精密化の統計情報

実験手法:ELECTRON MICROSCOPY

格子定数 [Å]458.112458.112458.112
格子定数 [度]90.0090.0090.00
空間群P 1
分解能 [Å] (低 - 高)458.11 - 3.50
最も高い分解能シェルの値3.591 - 3.500
R-work0.38380
最も高い分解能シェルの値0.589
結合長の平均二乗偏差(RMSD) [Å]0.005
結合角の平均二乗偏差(RMSD) [度]0.947

回折データの統計情報

分解能 [Å] (低 - 高) -
最も高い分解能シェルの値 -

結晶化条件

結晶ID方法pHpHの範囲温度単位

結晶化試薬

ID結晶ID濃度試薬名濃度 (単位)詳細
文献の結晶化試薬*
ID結晶ID溶液試薬名濃度 (単位) (単位)詳細
注釈情報は下記文献より抽出しています*

> 機能情報

?

GO(遺伝子オントロジー)由来の情報

鎖名GO(遺伝子オントロジー)id名前空間内容
w0043023molecular_functionribosomal large subunit binding
w0019843molecular_functionrRNA binding
w0000049molecular_functiontRNA binding
w0072344biological_processrescue of stalled ribosome
v0005829cellular_componentcytosol
v0016149molecular_functiontranslation release factor activity, codon specific
v0006415biological_processtranslational termination
J0005829cellular_componentcytosol
J0022625cellular_componentcytosolic large ribosomal subunit
J0019843molecular_functionrRNA binding
J0003735molecular_functionstructural constituent of ribosome
J0000027biological_processribosomal large subunit assembly
J0015968biological_processstringent response
J0006415biological_processtranslational termination
K0005829cellular_componentcytosol
K0022625cellular_componentcytosolic large ribosomal subunit
K0070180molecular_functionlarge ribosomal subunit rRNA binding
K0003729molecular_functionmRNA binding
K0003735molecular_functionstructural constituent of ribosome
K0008270molecular_functionzinc ion binding
K0017148biological_processnegative regulation of translation
K0006412biological_processtranslation
L0005829cellular_componentcytosol
L0022625cellular_componentcytosolic large ribosomal subunit
L0070180molecular_functionlarge ribosomal subunit rRNA binding
L0003735molecular_functionstructural constituent of ribosome
L0006412biological_processtranslation
M0022625cellular_componentcytosolic large ribosomal subunit
M0019843molecular_functionrRNA binding
M0003735molecular_functionstructural constituent of ribosome
M0006412biological_processtranslation
N0022625cellular_componentcytosolic large ribosomal subunit
N0019843molecular_functionrRNA binding
N0003735molecular_functionstructural constituent of ribosome
N0000049molecular_functiontRNA binding
N0000027biological_processribosomal large subunit assembly
N0006412biological_processtranslation
O0005829cellular_componentcytosol
O0022625cellular_componentcytosolic large ribosomal subunit
O0003735molecular_functionstructural constituent of ribosome
O0000027biological_processribosomal large subunit assembly
O0006412biological_processtranslation
P0005829cellular_componentcytosol
P0022625cellular_componentcytosolic large ribosomal subunit
P0008097molecular_function5S rRNA binding
P0003735molecular_functionstructural constituent of ribosome
P0006412biological_processtranslation
Q0005829cellular_componentcytosol
Q0022625cellular_componentcytosolic large ribosomal subunit
Q0070180molecular_functionlarge ribosomal subunit rRNA binding
Q0003735molecular_functionstructural constituent of ribosome
Q0000027biological_processribosomal large subunit assembly
Q0006412biological_processtranslation
R0005829cellular_componentcytosol
R0022625cellular_componentcytosolic large ribosomal subunit
R0070180molecular_functionlarge ribosomal subunit rRNA binding
R0003729molecular_functionmRNA binding
R0003735molecular_functionstructural constituent of ribosome
R0000900molecular_functiontranslation repressor activity, nucleic acid binding
R0000027biological_processribosomal large subunit assembly
R0006412biological_processtranslation
S0005829cellular_componentcytosol
S0022625cellular_componentcytosolic large ribosomal subunit
S0019843molecular_functionrRNA binding
S0003735molecular_functionstructural constituent of ribosome
S0006412biological_processtranslation
T0005829cellular_componentcytosol
T0022625cellular_componentcytosolic large ribosomal subunit
T0015934cellular_componentlarge ribosomal subunit
T0042788cellular_componentpolysomal ribosome
T0019843molecular_functionrRNA binding
T0003735molecular_functionstructural constituent of ribosome
T0046677biological_processresponse to antibiotic
T0042255biological_processribosome assembly
T0006412biological_processtranslation
U0022625cellular_componentcytosolic large ribosomal subunit
U0003723molecular_functionRNA binding
U0019843molecular_functionrRNA binding
U0003735molecular_functionstructural constituent of ribosome
U0000027biological_processribosomal large subunit assembly
U0006412biological_processtranslation
V0005829cellular_componentcytosol
V0022625cellular_componentcytosolic large ribosomal subunit
V0019843molecular_functionrRNA binding
V0003735molecular_functionstructural constituent of ribosome
V0000027biological_processribosomal large subunit assembly
V0006412biological_processtranslation
W0005829cellular_componentcytosol
W0022625cellular_componentcytosolic large ribosomal subunit
W0008097molecular_function5S rRNA binding
W0003735molecular_functionstructural constituent of ribosome
W0017148biological_processnegative regulation of translation
W0009314biological_processresponse to radiation
W0000027biological_processribosomal large subunit assembly
W0006412biological_processtranslation
X0022625cellular_componentcytosolic large ribosomal subunit
X0043022molecular_functionribosome binding
X0019843molecular_functionrRNA binding
X0003735molecular_functionstructural constituent of ribosome
X0000049molecular_functiontRNA binding
X1902626biological_processassembly of large subunit precursor of preribosome
X0090070biological_processpositive regulation of ribosome biogenesis
X0001558biological_processregulation of cell growth
X0000027biological_processribosomal large subunit assembly
X0006412biological_processtranslation
Y0005829cellular_componentcytosol
Y0022625cellular_componentcytosolic large ribosomal subunit
Y0019843molecular_functionrRNA binding
Y0003735molecular_functionstructural constituent of ribosome
Y0000027biological_processribosomal large subunit assembly
Y0006412biological_processtranslation
Z0022625cellular_componentcytosolic large ribosomal subunit
Z0019843molecular_functionrRNA binding
Z0003735molecular_functionstructural constituent of ribosome
Z0000027biological_processribosomal large subunit assembly
Z0006412biological_processtranslation
C0005829cellular_componentcytosol
C0022625cellular_componentcytosolic large ribosomal subunit
C0003723molecular_functionRNA binding
C0019843molecular_functionrRNA binding
C0003735molecular_functionstructural constituent of ribosome
C0016740molecular_functiontransferase activity
C0008270molecular_functionzinc ion binding
C0002181biological_processcytoplasmic translation
C0000027biological_processribosomal large subunit assembly
00022625cellular_componentcytosolic large ribosomal subunit
00003735molecular_functionstructural constituent of ribosome
00000027biological_processribosomal large subunit assembly
00006412biological_processtranslation
10005829cellular_componentcytosol
10022625cellular_componentcytosolic large ribosomal subunit
10003735molecular_functionstructural constituent of ribosome
10009314biological_processresponse to radiation
10000302biological_processresponse to reactive oxygen species
10000027biological_processribosomal large subunit assembly
10006412biological_processtranslation
20005829cellular_componentcytosol
20022625cellular_componentcytosolic large ribosomal subunit
20003735molecular_functionstructural constituent of ribosome
20000049molecular_functiontRNA binding
20046677biological_processresponse to antibiotic
20000027biological_processribosomal large subunit assembly
20006412biological_processtranslation
30005840cellular_componentribosome
30003735molecular_functionstructural constituent of ribosome
30006412biological_processtranslation
40022625cellular_componentcytosolic large ribosomal subunit
40003735molecular_functionstructural constituent of ribosome
40006412biological_processtranslation
50022625cellular_componentcytosolic large ribosomal subunit
50003735molecular_functionstructural constituent of ribosome
50006412biological_processtranslation
D0005829cellular_componentcytosol
D0022625cellular_componentcytosolic large ribosomal subunit
D0019843molecular_functionrRNA binding
D0003735molecular_functionstructural constituent of ribosome
D0000027biological_processribosomal large subunit assembly
D0006412biological_processtranslation
E0005829cellular_componentcytosol
E0022625cellular_componentcytosolic large ribosomal subunit
E0015934cellular_componentlarge ribosomal subunit
E0042788cellular_componentpolysomal ribosome
E0032993cellular_componentprotein-DNA complex
E0001217molecular_functionbacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding
E0060698molecular_functionendoribonuclease inhibitor activity
E0003723molecular_functionRNA binding
E0019843molecular_functionrRNA binding
E0003735molecular_functionstructural constituent of ribosome
E0030371molecular_functiontranslation repressor activity
E0006353biological_processDNA-templated transcription, termination
E0060702biological_processnegative regulation of endoribonuclease activity
E0045892biological_processnegative regulation of transcription, DNA-templated
E0017148biological_processnegative regulation of translation
E0046677biological_processresponse to antibiotic
E0042255biological_processribosome assembly
E0006412biological_processtranslation
F0005829cellular_componentcytosol
F0022625cellular_componentcytosolic large ribosomal subunit
F0008097molecular_function5S rRNA binding
F0003735molecular_functionstructural constituent of ribosome
F0000049molecular_functiontRNA binding
F0000027biological_processribosomal large subunit assembly
F0006412biological_processtranslation
G0005829cellular_componentcytosol
G0022625cellular_componentcytosolic large ribosomal subunit
G0070180molecular_functionlarge ribosomal subunit rRNA binding
G0003723molecular_functionRNA binding
G0003735molecular_functionstructural constituent of ribosome
G0002181biological_processcytoplasmic translation
G0046677biological_processresponse to antibiotic
G0000027biological_processribosomal large subunit assembly
H0005829cellular_componentcytosol
H0022625cellular_componentcytosolic large ribosomal subunit
H0070180molecular_functionlarge ribosomal subunit rRNA binding
H0003735molecular_functionstructural constituent of ribosome
H0006412biological_processtranslation
j0005829cellular_componentcytosol
j0022627cellular_componentcytosolic small ribosomal subunit
j0003723molecular_functionRNA binding
j0003735molecular_functionstructural constituent of ribosome
j0001072molecular_functiontranscription antitermination factor activity, RNA binding
j0031564biological_processtranscription antitermination
j0006412biological_processtranslation
k0005829cellular_componentcytosol
k0022627cellular_componentcytosolic small ribosomal subunit
k0048027molecular_functionmRNA 5'-UTR binding
k0070181molecular_functionsmall ribosomal subunit rRNA binding
k0003735molecular_functionstructural constituent of ribosome
k0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
k0000028biological_processribosomal small subunit assembly
k0006412biological_processtranslation
l0005829cellular_componentcytosol
l0022627cellular_componentcytosolic small ribosomal subunit
l0034336molecular_functionmisfolded RNA binding
l0019843molecular_functionrRNA binding
l0003735molecular_functionstructural constituent of ribosome
l0000049molecular_functiontRNA binding
l0000372biological_processGroup I intron splicing
l1990145biological_processmaintenance of translational fidelity
l0033120biological_processpositive regulation of RNA splicing
l0046677biological_processresponse to antibiotic
l0034337biological_processRNA folding
l0006412biological_processtranslation
m0005829cellular_componentcytosol
m0022627cellular_componentcytosolic small ribosomal subunit
m0019843molecular_functionrRNA binding
m0003735molecular_functionstructural constituent of ribosome
m0000049molecular_functiontRNA binding
m0042254biological_processribosome biogenesis
m0006412biological_processtranslation
n0022627cellular_componentcytosolic small ribosomal subunit
n0003735molecular_functionstructural constituent of ribosome
n0000028biological_processribosomal small subunit assembly
n0006412biological_processtranslation
o0005829cellular_componentcytosol
o0022627cellular_componentcytosolic small ribosomal subunit
o0019843molecular_functionrRNA binding
o0003735molecular_functionstructural constituent of ribosome
o0006378biological_processmRNA polyadenylation
o0006417biological_processregulation of translation
o0000028biological_processribosomal small subunit assembly
o0006412biological_processtranslation
p0022627cellular_componentcytosolic small ribosomal subunit
p0004520molecular_functionendodeoxyribonuclease activity
p0000400molecular_functionfour-way junction DNA binding
p0003735molecular_functionstructural constituent of ribosome
p0000028biological_processribosomal small subunit assembly
p0006412biological_processtranslation
q0022627cellular_componentcytosolic small ribosomal subunit
q0019843molecular_functionrRNA binding
q0070181molecular_functionsmall ribosomal subunit rRNA binding
q0003735molecular_functionstructural constituent of ribosome
q0046677biological_processresponse to antibiotic
q0000028biological_processribosomal small subunit assembly
q0006412biological_processtranslation
r0005829cellular_componentcytosol
r0022627cellular_componentcytosolic small ribosomal subunit
r0048027molecular_functionmRNA 5'-UTR binding
r0070181molecular_functionsmall ribosomal subunit rRNA binding
r0003735molecular_functionstructural constituent of ribosome
r0006412biological_processtranslation
s0005829cellular_componentcytosol
s0022627cellular_componentcytosolic small ribosomal subunit
s0019843molecular_functionrRNA binding
s0003735molecular_functionstructural constituent of ribosome
s0000049molecular_functiontRNA binding
s0000028biological_processribosomal small subunit assembly
s0006412biological_processtranslation
t0005829cellular_componentcytosol
t0022627cellular_componentcytosolic small ribosomal subunit
t0008073molecular_functionornithine decarboxylase inhibitor activity
t0070181molecular_functionsmall ribosomal subunit rRNA binding
t0003735molecular_functionstructural constituent of ribosome
t0000028biological_processribosomal small subunit assembly
t0006412biological_processtranslation
u0005829cellular_componentcytosol
u0022627cellular_componentcytosolic small ribosomal subunit
u0019843molecular_functionrRNA binding
u0003735molecular_functionstructural constituent of ribosome
u0000028biological_processribosomal small subunit assembly
u0006412biological_processtranslation
b0022627cellular_componentcytosolic small ribosomal subunit
b0003735molecular_functionstructural constituent of ribosome
b0008270molecular_functionzinc ion binding
b0000028biological_processribosomal small subunit assembly
b0006412biological_processtranslation
c0005829cellular_componentcytosol
c0022627cellular_componentcytosolic small ribosomal subunit
c0019843molecular_functionrRNA binding
c0003735molecular_functionstructural constituent of ribosome
c0002181biological_processcytoplasmic translation
c0000028biological_processribosomal small subunit assembly
d0005829cellular_componentcytosol
d0022627cellular_componentcytosolic small ribosomal subunit
d0048027molecular_functionmRNA 5'-UTR binding
d0019843molecular_functionrRNA binding
d0003735molecular_functionstructural constituent of ribosome
d0000900molecular_functiontranslation repressor activity, nucleic acid binding
d0006353biological_processDNA-templated transcription, termination
d1990145biological_processmaintenance of translational fidelity
d0045947biological_processnegative regulation of translational initiation
d0045903biological_processpositive regulation of translational fidelity
d0046677biological_processresponse to antibiotic
d0000028biological_processribosomal small subunit assembly
d0031564biological_processtranscription antitermination
e0005829cellular_componentcytosol
e0022627cellular_componentcytosolic small ribosomal subunit
e0019843molecular_functionrRNA binding
e0003735molecular_functionstructural constituent of ribosome
e1990145biological_processmaintenance of translational fidelity
e0046677biological_processresponse to antibiotic
e0000028biological_processribosomal small subunit assembly
f0005829cellular_componentcytosol
f0022627cellular_componentcytosolic small ribosomal subunit
f0048027molecular_functionmRNA 5'-UTR binding
f0070181molecular_functionsmall ribosomal subunit rRNA binding
f0003735molecular_functionstructural constituent of ribosome
f0006412biological_processtranslation
g0005829cellular_componentcytosol
g0022627cellular_componentcytosolic small ribosomal subunit
g0016020cellular_componentmembrane
g0003729molecular_functionmRNA binding
g0019843molecular_functionrRNA binding
g0003735molecular_functionstructural constituent of ribosome
g0000049molecular_functiontRNA binding
g0017148biological_processnegative regulation of translation
g0000028biological_processribosomal small subunit assembly
g0006412biological_processtranslation
h0005829cellular_componentcytosol
h0022627cellular_componentcytosolic small ribosomal subunit
h0019843molecular_functionrRNA binding
h0003735molecular_functionstructural constituent of ribosome
h0043488biological_processregulation of mRNA stability
h0006417biological_processregulation of translation
h0000028biological_processribosomal small subunit assembly
h0006412biological_processtranslation
i0005829cellular_componentcytosol
i0022627cellular_componentcytosolic small ribosomal subunit
i0003723molecular_functionRNA binding
i0003735molecular_functionstructural constituent of ribosome
i0000049molecular_functiontRNA binding
i0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
i0006412biological_processtranslation
?

PDBデータベースに由来する情報

site_id残基数詳細
AC11binding site for residue MG A 3001
鎖名残基
AA28

AC21binding site for residue MG A 3002
鎖名残基
AU120

AC32binding site for residue MG A 3003
鎖名残基
AG450
EGLY81

AC42binding site for residue MG A 3004
鎖名残基
AU566
AU567

AC51binding site for residue MG A 3005
鎖名残基
AA574

AC61binding site for residue MG A 3007
鎖名残基
AA608

AC72binding site for residue MG A 3008
鎖名残基
AC731
AG760

AC81binding site for residue MG A 3009
鎖名残基
APSU746

AC92binding site for residue MG A 3010
鎖名残基
AA751
AA1614

AD15binding site for residue MG A 3011
鎖名残基
AA782
AA783
AG784
AA2589
CALA224

AD22binding site for residue MG A 3012
鎖名残基
AG784
AG2588

AD31binding site for residue MG A 3013
鎖名残基
AG798

AD41binding site for residue MG A 3014
鎖名残基
AA802

AD51binding site for residue MG A 3015
鎖名残基
AA945

AD63binding site for residue MG A 3016
鎖名残基
AC948
AG962
AU963

AD71binding site for residue MG A 3017
鎖名残基
AA1156

AD82binding site for residue MG A 3018
鎖名残基
AC817
AG1187

AD93binding site for residue MG A 3020
鎖名残基
AA1268
AA2005
AC2006

AE15binding site for residue MG A 3021
鎖名残基
AC1270
AG1271
AA1272
AU1647
AU1648

AE21binding site for residue MG A 3022
鎖名残基
AU1313

AE32binding site for residue MG A 3023
鎖名残基
AG1332
AG1333

AE44binding site for residue MG A 3024
鎖名残基
AA1393
AU1394
AA1603
AC1604

AE54binding site for residue MG A 3025
鎖名残基
AC1306
AA1395
AA1603
AC1604

AE62binding site for residue MG A 3026
鎖名残基
AA1616
AU1647

AE73binding site for residue MG A 3027
鎖名残基
AA1664
AG1666
AG1667

AE81binding site for residue MG A 3028
鎖名残基
AC1986

AE93binding site for residue MG A 3029
鎖名残基
AC1670
AU1671
AG2550

AF12binding site for residue MG A 3030
鎖名残基
AC1774
AA1786

AF21binding site for residue MG A 3031
鎖名残基
AG1776

AF32binding site for residue MG A 3032
鎖名残基
AA1900
AA1970

AF42binding site for residue MG A 3033
鎖名残基
AC2025
AU2034

AF52binding site for residue MG A 3034
鎖名残基
AG2056
AG2057

AF62binding site for residue MG A 3035
鎖名残基
AG2061
AG2502

AF71binding site for residue MG A 3036
鎖名残基
AA2062

AF81binding site for residue MG A 3037
鎖名残基
AU2075

AF93binding site for residue MG A 3038
鎖名残基
AA2247
AC2248
AU2249

AG13binding site for residue MG A 3039
鎖名残基
AA2267
AA2270
AU2272

AG22binding site for residue MG A 3040
鎖名残基
AA2518
AA2541

AG31binding site for residue MG A 3041
鎖名残基
AG2588

AG43binding site for residue MG A 3042
鎖名残基
AA990
AC991
AG1186

AG52binding site for residue MG A 3043
鎖名残基
AA1327
AA1328

AG62binding site for residue MG A 3044
鎖名残基
AA1359
AG1360

AG72binding site for residue MG A 3045
鎖名残基
AA1439
AU1440

AG83binding site for residue MG A 3047
鎖名残基
AG1300
AA1635
AU1636

AG93binding site for residue MG A 3048
鎖名残基
AA743
AC1658
DHIS140

AH15binding site for residue MG A 3049
鎖名残基
AG2447
AA2448
AA2497
AOMC2498
AC2499

AH23binding site for residue MG A 3050
鎖名残基
AA1780
AU1782
AA1783

AH34binding site for residue MG A 3051
鎖名残基
AA730
AC731
AA761
AU762

AH43binding site for residue MG A 3052
鎖名残基
AC740
AA1783
AA1784

AH54binding site for residue MG A 3053
鎖名残基
AG2581
AG2582
AG2583
AU2584

AH64binding site for residue MG A 3054
鎖名残基
AC2507
AC2573
AG2574
AC2575

AH73binding site for residue MG A 3055
鎖名残基
AC192
AA199
AU2243

AH83binding site for residue MG A 3056
鎖名残基
AG1828
CARG221
CARG238

AH92binding site for residue MG A 3057
鎖名残基
AA1265
AU2615

AI14binding site for residue MG A 3058
鎖名残基
AG194
AA195
AA197
AC198

AI22binding site for residue MG A 3059
鎖名残基
AC1675
AA1676

AI31binding site for residue MG A 3060
鎖名残基
AA973

AI41binding site for residue MG A 3061
鎖名残基
AU2593

AI53binding site for residue MG A 3062
鎖名残基
AU832
AA943
MGLY37

AI62binding site for residue MG A 3063
鎖名残基
AG2004
OASN11

AI73binding site for residue MG A 3064
鎖名残基
AG578
AU2017
AG2018

AI82binding site for residue MG A 3065
鎖名残基
AU963
AOMC2498

AI92binding site for residue MG A 3066
鎖名残基
AA1664
AA1665

AJ14binding site for residue MG A 3067
鎖名残基
AC678
AG776
AA2071
AC2072

AJ22binding site for residue MG A 3068
鎖名残基
AA1189
AG1190

AJ32binding site for residue MG A 3069
鎖名残基
AG1949
AU1955

AJ45binding site for residue MG A 3070
鎖名残基
AA1669
AC1670
AU1671
AG2550
AC2551

AJ53binding site for residue MG A 3071
鎖名残基
AC944
AA945
AC946

AJ62binding site for residue MG A 3072
鎖名残基
AG1968
AG2592

AJ74binding site for residue MG A 3073
鎖名残基
AU826
AC2427
AG2428
AG2429

AJ82binding site for residue MG A 3074
鎖名残基
AC1315
AG1332

AJ92binding site for residue MG A 3075
鎖名残基
AG831
AA945

AK11binding site for residue MG A 3077
鎖名残基
AU1995

AK21binding site for residue MG A 3078
鎖名残基
AU1827

AK33binding site for residue MG A 3079
鎖名残基
AG1823
AG1824
CHIS53

AK43binding site for residue MG A 3080
鎖名残基
AU810
AU811
AA1253

AK53binding site for residue MG A 3081
鎖名残基
AC31
AC1200
AG1239

AK62binding site for residue MG A 3082
鎖名残基
AU2074
AG2239

AK73binding site for residue MG A 3083
鎖名残基
AA1342
AG1343
AC1398

AK82binding site for residue MG A 3084
鎖名残基
AA1970
AU1971

AK92binding site for residue MG A 3085
鎖名残基
AA739
AU1779

AL12binding site for residue MG A 3086
鎖名残基
AA1938
AC1957

AL21binding site for residue MG A 3088
鎖名残基
AG1945

AL32binding site for residue MG A 3089
鎖名残基
AA1269
AA2005

AL41binding site for residue MG A 3090
鎖名残基
AG1288

AL51binding site for residue MG A 3091
鎖名残基
AG2508

AL62binding site for residue MG A 3092
鎖名残基
AC2579
AC2611

AL75binding site for residue MG A 3093
鎖名残基
AA2052
AG2053
AC2575
AG2576
AA2577

AL82binding site for residue MG A 3094
鎖名残基
AA743
AG2581

AL91binding site for residue MG A 3095
鎖名残基
AA975

AM12binding site for residue MG A 3098
鎖名残基
AA2051
AG2578

AM21binding site for residue MG A 3099
鎖名残基
AC867

AM33binding site for residue MG B 201
鎖名残基
BA57
BA58
BA59

AM43binding site for residue MG B 202
鎖名残基
BC93
BA94
BU95

AM52binding site for residue MG B 203
鎖名残基
BG100
BA101

AM61binding site for residue MG B 204
鎖名残基
BG16

AM75binding site for residue ZN 5 101
鎖名残基
5CYS11
5CYS14
5CYS27
5GLU30
5HIS33

AM82binding site for residue MG a 1601
鎖名残基
aG785
aU793

AM92binding site for residue MG a 1602
鎖名残基
aA572
aA573

AN14binding site for residue MG a 1603
鎖名残基
aU571
aA572
aA573
aA574

AN21binding site for residue MG a 1604
鎖名残基
aC576

AN32binding site for residue MG a 1605
鎖名残基
aG731
aA816

AN41binding site for residue MG a 1606
鎖名残基
aA768

AN52binding site for residue MG a 1607
鎖名残基
aC651
aG752

AN66binding site for residue MG a 1608
鎖名残基
aG115
aA116
aG117
aU118
aA288
aG289

AN73binding site for residue MG a 1609
鎖名残基
aC507
aA509
aA510

AN84binding site for residue MG a 1610
鎖名残基
aA559
aA560
aU562
aA563

AN91binding site for residue MG a 1612
鎖名残基
aA781

AO12binding site for residue MG a 1613
鎖名残基
aG577
aA814

AO24binding site for residue MG a 1614
鎖名残基
aC857
aG858
aC868
aG869

AO32binding site for residue MG a 1615
鎖名残基
aU891
aA892

AO43binding site for residue MG a 1616
鎖名残基
aG1053
aC1054
aA1197

AO55binding site for residue MG a 1617
鎖名残基
aUR31498
aA1499
aA1500
aG1504
aG1505

AO65binding site for residue MG a 1618
鎖名残基
aA1500
aC1501
aG1504
aG1505
aA1508

AO72binding site for residue MG a 1619
鎖名残基
aG944
aG945

AO82binding site for residue MG a 1620
鎖名残基
aG945
aC1230

?

「HETATM」原子の座標から抽出されたリガンド結合部位

site_id残基数詳細
OMC_5u4i_A_249812O2'-METHYLYCYTIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AU569-G570OMC: O2'-METHYLYCYTIDINE-5'-MONOPHOSPHATE
AA2030-A2031OMC: O2'-METHYLYCYTIDINE-5'-MONOPHOSPHATE
AG2447-U2449OMC: O2'-METHYLYCYTIDINE-5'-MONOPHOSPHATE
AG2454-G2455OMC: O2'-METHYLYCYTIDINE-5'-MONOPHOSPHATE
AC2496-A2497OMC: O2'-METHYLYCYTIDINE-5'-MONOPHOSPHATE
AC2499OMC: O2'-METHYLYCYTIDINE-5'-MONOPHOSPHATE

PSU_5u4i_A_250413PSEUDOURIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AU576PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AC2055-G2056PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG2447PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA2451-A2453PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AU2500-C2501PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA2503PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG2505-U2506PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA2572PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE

2MG_5u4i_A_2445122N-METHYLGUANOSINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AG6742MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AC806-U8072MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AG8302MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AA20602MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AC2064-C20662MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AG24442MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AG24462MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AU24492MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
EARG692MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE

1MG_5u4i_A_74581N-METHYLGUANOSINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AU7441MG: 1N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AG748-A7501MG: 1N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AA7531MG: 1N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AU16571MG: 1N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AC26101MG: 1N-METHYLGUANOSINE-5'-MONOPHOSPHATE
DLEU1381MG: 1N-METHYLGUANOSINE-5'-MONOPHOSPHATE

5MU_5u4i_A_747135-METHYLURIDINE 5'-MONOPHOSPHATE binding site
鎖名残基ligand
AG7485MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
AA2013-A20155MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
AC2611-U26135MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
TARG88-LYS905MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
TARG925MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
TASP945MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
1ALA25MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE

PSU_5u4i_A_7465PSEUDOURIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AG748PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AC2610-C2612PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
TLYS90PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE

PSU_5u4i_A_95514PSEUDOURIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AG954PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG956PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG962-U963PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG2250PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA2274PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG2276PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
NMET12-LYS14PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
NLYS76PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
NMET82PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
NGLY85-LYS86PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE

PSU_5u4i_A_24578PSEUDOURIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AC957PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA959-C961PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AC2456PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG2458PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG2494-G2495PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE

PSU_5u4i_A_258013PSEUDOURIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AA1672PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG2508-G2509PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG2576PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AC2579PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AG2581-G2582PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AC2610-C2611PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
DHIS134-SER137PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE

OMU_5u4i_A_255212O2'-METHYLURIDINE 5'-MONOPHOSPHATE binding site
鎖名残基ligand
AG1673OMU: O2'-METHYLURIDINE 5'-MONOPHOSPHATE
AG1954-U1956OMU: O2'-METHYLURIDINE 5'-MONOPHOSPHATE
AC1985OMU: O2'-METHYLURIDINE 5'-MONOPHOSPHATE
AC2551OMU: O2'-METHYLURIDINE 5'-MONOPHOSPHATE
AG2553-G2557OMU: O2'-METHYLURIDINE 5'-MONOPHOSPHATE
vSER247OMU: O2'-METHYLURIDINE 5'-MONOPHOSPHATE

PSU_5u4i_A_26056PSEUDOURIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AA1786PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA1938PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA2589-A2590PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AU2604PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AC2606PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE

2MG_5u4i_A_1835102N-METHYLGUANOSINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AU18342MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AC18362MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AA19002MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AG1904-C19052MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AG1930-U19312MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
AA1969-A19702MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aC7832MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE

PSU_5u4i_A_19115PSEUDOURIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AG1910PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA1912PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA1918-C1920PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE

PSU_5u4i_A_19174PSEUDOURIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AA1912PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA1916PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
AA1918PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
aA1408PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE

5MC_5u4i_a_140765-METHYLCYTIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AA19125MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
AA19195MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
aU14065MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
aA14085MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
aG1494-U14955MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE

2MG_5u4i_a_151662N-METHYLGUANOSINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AU19312MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aC7832MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aU7932MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aG15152MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aG15172MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aC15202MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE

5MC_5u4i_A_196275-METHYLCYTIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AG1935-A19365MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
AU19405MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
AC19615MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
AU1963-G19645MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
aU14855MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE

5MU_5u4i_A_1939105-METHYLURIDINE 5'-MONOPHOSPHATE binding site
鎖名残基ligand
AA1937-A19385MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
AU19405MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
AA1966-C19675MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
AC19745MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
AC2591-G25925MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE
AG2603-U26045MU: 5-METHYLURIDINE 5'-MONOPHOSPHATE

OMG_5u4i_A_225111O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
AC2064-C2065OMG: O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE
AG2250OMG: O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE
AG2252OMG: O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE
AU2449-A2450OMG: O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE
AA2497OMG: O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE
NARG81OMG: O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE
xC74-A76OMG: O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE

MEQ_5u4i_v_25212N5-METHYLGLUTAMINE binding site
鎖名残基ligand
AA2451-C2452MEQ: N5-METHYLGLUTAMINE
AG2505-U2506MEQ: N5-METHYLGLUTAMINE
AU2585MEQ: N5-METHYLGLUTAMINE
vGLY250-GLY251MEQ: N5-METHYLGLUTAMINE
vHIS253-ARG256MEQ: N5-METHYLGLUTAMINE
xA76MEQ: N5-METHYLGLUTAMINE

PSU_5u4i_a_5167PSEUDOURIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
aG515PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
aG517PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
aC519-A520PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
aA532-A533PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE
aC536PSU: PSEUDOURIDINE-5'-MONOPHOSPHATE

2MG_5u4i_a_120772N-METHYLGUANOSINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
aA5322MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aG1050-U10522MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aG12062MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aC12082MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
cTHR1922MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE

UR3_5u4i_a_1498123-METHYLURIDINE-5'-MONOPHOSHATE binding site
鎖名残基ligand
aA790-A792UR3: 3-METHYLURIDINE-5'-MONOPHOSHATE
aC1403-C1404UR3: 3-METHYLURIDINE-5'-MONOPHOSHATE
aG1497UR3: 3-METHYLURIDINE-5'-MONOPHOSHATE
aA1499-A1500UR3: 3-METHYLURIDINE-5'-MONOPHOSHATE
aG1505UR3: 3-METHYLURIDINE-5'-MONOPHOSHATE
zA46-G48UR3: 3-METHYLURIDINE-5'-MONOPHOSHATE

MA6_5u4i_a_151876N-DIMETHYLADENOSINE-5'-MONOPHOSHATE binding site
鎖名残基ligand
aG791MA6: 6N-DIMETHYLADENOSINE-5'-MONOPHOSHATE
aU793MA6: 6N-DIMETHYLADENOSINE-5'-MONOPHOSHATE
aG1405-U1406MA6: 6N-DIMETHYLADENOSINE-5'-MONOPHOSHATE
aC1496-G1497MA6: 6N-DIMETHYLADENOSINE-5'-MONOPHOSHATE
aG1517MA6: 6N-DIMETHYLADENOSINE-5'-MONOPHOSHATE

MA6_5u4i_a_151976N-DIMETHYLADENOSINE-5'-MONOPHOSHATE binding site
鎖名残基ligand
aG791-A792MA6: 6N-DIMETHYLADENOSINE-5'-MONOPHOSHATE
aC1404-G1405MA6: 6N-DIMETHYLADENOSINE-5'-MONOPHOSHATE
aG1497MA6: 6N-DIMETHYLADENOSINE-5'-MONOPHOSHATE
aA1499MA6: 6N-DIMETHYLADENOSINE-5'-MONOPHOSHATE
aC1520MA6: 6N-DIMETHYLADENOSINE-5'-MONOPHOSHATE

2MG_5u4i_a_96692N-METHYLGUANOSINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
aU9652MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aA968-A9692MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
aC14002MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
iLYS129-ARG1302MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
vPRO2062MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE
xC34-A352MG: 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE

5MC_5u4i_a_96775-METHYLCYTIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
aU9655MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
aA968-C9705MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE
iPHE127-LYS1295MC: 5-METHYLCYTIDINE-5'-MONOPHOSPHATE

4OC_5u4i_a_1402104N,O2'-METHYLCYTIDINE-5'-MONOPHOSPHATE binding site
鎖名残基ligand
aA1394-C13974OC: 4N,O2'-METHYLCYTIDINE-5'-MONOPHOSPHATE
aG14014OC: 4N,O2'-METHYLCYTIDINE-5'-MONOPHOSPHATE
aC14034OC: 4N,O2'-METHYLCYTIDINE-5'-MONOPHOSPHATE
aA1500-C15014OC: 4N,O2'-METHYLCYTIDINE-5'-MONOPHOSPHATE
zU47-G484OC: 4N,O2'-METHYLCYTIDINE-5'-MONOPHOSPHATE

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UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id残基数詳細
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SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id残基数詳細
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CSAにおける酵素触媒機能の情報

site_id残基数詳細

> 相同蛋白質

Sequence navigator - 5u4i: Chain A
Sequence navigator - 5u4i: Chain B
Sequence navigator - 5u4i: Chain C
Sequence navigator - 5u4i: Chain D
Sequence navigator - 5u4i: Chain E
Sequence navigator - 5u4i: Chain F
Sequence navigator - 5u4i: Chain G
Sequence navigator - 5u4i: Chain H
Sequence navigator - 5u4i: Chain J
Sequence navigator - 5u4i: Chain K
Sequence navigator - 5u4i: Chain L
Sequence navigator - 5u4i: Chain M
Sequence navigator - 5u4i: Chain N
Sequence navigator - 5u4i: Chain O
Sequence navigator - 5u4i: Chain P
Sequence navigator - 5u4i: Chain Q
Sequence navigator - 5u4i: Chain R
Sequence navigator - 5u4i: Chain S
Sequence navigator - 5u4i: Chain T
Sequence navigator - 5u4i: Chain U
Sequence navigator - 5u4i: Chain V
Sequence navigator - 5u4i: Chain W
Sequence navigator - 5u4i: Chain X
Sequence navigator - 5u4i: Chain Y
Sequence navigator - 5u4i: Chain Z
Sequence navigator - 5u4i: Chain 0
Sequence navigator - 5u4i: Chain 1
Sequence navigator - 5u4i: Chain 2
Sequence navigator - 5u4i: Chain 3
Sequence navigator - 5u4i: Chain 4
Sequence navigator - 5u4i: Chain 5
Sequence navigator - 5u4i: Chain a
Sequence navigator - 5u4i: Chain b
Sequence navigator - 5u4i: Chain c
Sequence navigator - 5u4i: Chain d
Sequence navigator - 5u4i: Chain e
Sequence navigator - 5u4i: Chain f
Sequence navigator - 5u4i: Chain g
Sequence navigator - 5u4i: Chain h
Sequence navigator - 5u4i: Chain i
Sequence navigator - 5u4i: Chain j
Sequence navigator - 5u4i: Chain k
Sequence navigator - 5u4i: Chain l
Sequence navigator - 5u4i: Chain m
Sequence navigator - 5u4i: Chain n
Sequence navigator - 5u4i: Chain o
Sequence navigator - 5u4i: Chain p
Sequence navigator - 5u4i: Chain q
Sequence navigator - 5u4i: Chain r
Sequence navigator - 5u4i: Chain s
Sequence navigator - 5u4i: Chain t
Sequence navigator - 5u4i: Chain u
Sequence navigator - 5u4i: Chain v
Sequence navigator - 5u4i: Chain w
Sequence navigator - 5u4i: Chain x,y
Sequence navigator - 5u4i: Chain z

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