5U0C
Structure of Zika virus NS5 RNA polymerase domain
5U0C の概要
エントリーDOI | 10.2210/pdb5u0c/pdb |
分子名称 | NS5 RNA polymerase domain, ZINC ION (2 entities in total) |
機能のキーワード | rna polymerase, transferase |
由来する生物種 | Zika virus (strain Mr 766) (ZIKV) |
細胞内の位置 | Protein C: Virion . Peptide pr: Secreted . Small envelope protein M: Virion membrane ; Multi-pass membrane protein . Envelope protein E: Virion membrane ; Single-pass membrane protein . Non-structural protein 1: Secreted . Non-structural protein 2A: Host endoplasmic reticulum membrane ; Multi- pass membrane protein . Serine protease subunit NS2B: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Serine protease NS3: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Non-structural protein 4A: Host endoplasmic reticulum membrane ; Multi- pass membrane protein . Non-structural protein 4B: Host endoplasmic reticulum membrane ; Multi- pass membrane protein . RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side : Q32ZE1 |
タンパク質・核酸の鎖数 | 8 |
化学式量合計 | 591951.17 |
構造登録者 | |
主引用文献 | Zhao, B.,Yi, G.,Du, F.,Chuang, Y.C.,Vaughan, R.C.,Sankaran, B.,Kao, C.C.,Li, P. Structure and function of the Zika virus full-length NS5 protein. Nat Commun, 8:14762-14762, 2017 Cited by PubMed: 28345656DOI: 10.1038/ncomms14762 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード