5TZV
Binary complex crystal structure of DNA Polymerase Beta with G:T mismatch at the primer terminus
Replaces: 5J0VSummary for 5TZV
Entry DOI | 10.2210/pdb5tzv/pdb |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3'), ... (6 entities in total) |
Functional Keywords | dna polymerase, fidelity, mismatch extension, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 47798.84 |
Authors | Wilson, S.H.,Batra, V.K. (deposition date: 2016-11-22, release date: 2016-12-07, Last modification date: 2023-10-04) |
Primary citation | Batra, V.K.,Beard, W.A.,Pedersen, L.C.,Wilson, S.H. Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24:1863-1875, 2016 Cited by PubMed: 27642161DOI: 10.1016/j.str.2016.08.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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