5TYQ

Crystal structure of a holoenzyme methyltransferase involved in the biosynthesis of gentamicin

5TYQ の概要

• エントリーDOI: 10.2210/pdb5tyq/pdb
• 分子名称: Putative gentamicin methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: methyltransferase gentamicin biosynthesis sam, transferase
• 由来する生物種: Micromonospora echinospora
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37804.45

構造登録者

Bury, P.,Huang, F.,Leadlay, P.,Dias, M.V.B. (登録日: 2016-11-21, 公開日: 2017-11-01, 最終更新日: 2024-03-06)

• 主引用文献: Bury, P.D.S.,Huang, F.,Li, S.,Sun, Y.,Leadlay, P.F.,Dias, M.V.B.; Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis.; ACS Chem. Biol., 12:2779-2787, 2017; PubMed: 28876898; DOI: 10.1021/acschembio.7b00466

実験手法

X-RAY DIFFRACTION (2.163 Å)