5TYP
alpha-esterase-7 in complex with (3-bromo-4-methylphenyl)boronic acid
Summary for 5TYP
Entry DOI | 10.2210/pdb5typ/pdb |
Related | 5TYJ 5TYK 5TYL 5TYM 5TYN 5TYO |
Descriptor | Carboxylic ester hydrolase, (3-bromo-4-methylphenyl)boronic acid (3 entities in total) |
Functional Keywords | carboxylesterase, insecticide resistance, covalent inhibitor, organophosphate, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Lucilia cuprina (Green bottle fly) |
Total number of polymer chains | 1 |
Total formula weight | 66603.69 |
Authors | Correy, G.J.,Jackson, C.J. (deposition date: 2016-11-21, release date: 2017-12-06, Last modification date: 2023-10-04) |
Primary citation | Correy, G.J.,Zaidman, D.,Harmelin, A.,Carvalho, S.,Mabbitt, P.D.,Calaora, V.,James, P.J.,Kotze, A.C.,Jackson, C.J.,London, N. Overcoming insecticide resistance through computational inhibitor design. Proc.Natl.Acad.Sci.USA, 116:21012-21021, 2019 Cited by PubMed: 31575743DOI: 10.1073/pnas.1909130116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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