5TY1
Identification of a New Zinc Binding Chemotype by Fragment Screening
Summary for 5TY1
| Entry DOI | 10.2210/pdb5ty1/pdb |
| Related | 5TY8 5TY9 5TYA 5U0D 5U0E 5U0F 5U0G |
| Descriptor | Carbonic anhydrase 2, ZINC ION, (5R)-5-(2,4-dimethoxyphenyl)-1,3-oxazolidine-2,4-dione, ... (5 entities in total) |
| Functional Keywords | fragment screening, carbonic anhydrase, lyase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 29614.67 |
| Authors | Peat, T.S. (deposition date: 2016-11-18, release date: 2017-10-04, Last modification date: 2023-10-04) |
| Primary citation | Chrysanthopoulos, P.K.,Mujumdar, P.,Woods, L.A.,Dolezal, O.,Ren, B.,Peat, T.S.,Poulsen, S.A. Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60:7333-7349, 2017 Cited by PubMed: 28817930DOI: 10.1021/acs.jmedchem.7b00606 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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