5TUN
Crystal structure of uninhibited human Cathepsin K at 1.62 Angstrom resolution
Summary for 5TUN
Entry DOI | 10.2210/pdb5tun/pdb |
Descriptor | Cathepsin K (2 entities in total) |
Functional Keywords | cathepsin k, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 23523.48 |
Authors | Aguda, A.H.,Kruglyak, N.,Nguyen, N.T.,Law, S.,Bromme, D.,Brayer, G.D. (deposition date: 2016-11-06, release date: 2017-01-18, Last modification date: 2023-10-04) |
Primary citation | Law, S.,Andrault, P.M.,Aguda, A.H.,Nguyen, N.T.,Kruglyak, N.,Brayer, G.D.,Bromme, D. Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib. Biochem. J., 474:851-864, 2017 Cited by PubMed: 28049758DOI: 10.1042/BCJ20160985 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.62 Å) |
Structure validation
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