5TUD

Structural Insights into the Extracellular Recognition of the Human Serotonin 2B Receptor by an Antibody

Summary for 5TUD

• Entry DOI: 10.2210/pdb5tud/pdb
• Related: 4NC3
• Descriptor: 5-hydroxytryptamine receptor 2B,Soluble cytochrome b562 chimera, Anti-5-HT2B Fab light chain, Anti-5-HT2B Fab heavy chain, ... (4 entities in total)
• Functional Keywords: 7-tm, gpcr, fab, complex, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 201427.99

Authors

Ishchenko, A.,Wacker, D.,Kapoor, M.,Zhang, A.,Han, G.W.,Basu, S.,Boutet, S.,James, D.,Wang, D.,Weierstall, U.,Liu, W.,Katritch, V.,Stevens, R.C.,Cherezov, V. (deposition date: 2016-11-05, release date: 2017-07-26, Last modification date: 2023-10-04)

• Primary citation: Ishchenko, A.,Wacker, D.,Kapoor, M.,Zhang, A.,Han, G.W.,Basu, S.,Patel, N.,Messerschmidt, M.,Weierstall, U.,Liu, W.,Katritch, V.,Roth, B.L.,Stevens, R.C.,Cherezov, V.; Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody.; Proc. Natl. Acad. Sci. U.S.A., 114:8223-8228, 2017; PubMed: 28716900; DOI: 10.1073/pnas.1700891114

Experimental method

X-RAY DIFFRACTION (3 Å)