5TUD

Structural Insights into the Extracellular Recognition of the Human Serotonin 2B Receptor by an Antibody

5TUD の概要

• エントリーDOI: 10.2210/pdb5tud/pdb
• 関連するPDBエントリー: 4NC3
• 分子名称: 5-hydroxytryptamine receptor 2B,Soluble cytochrome b562 chimera, Anti-5-HT2B Fab light chain, Anti-5-HT2B Fab heavy chain, ... (4 entities in total)
• 機能のキーワード: 7-tm, gpcr, fab, complex, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 201427.99

構造登録者

Ishchenko, A.,Wacker, D.,Kapoor, M.,Zhang, A.,Han, G.W.,Basu, S.,Boutet, S.,James, D.,Wang, D.,Weierstall, U.,Liu, W.,Katritch, V.,Stevens, R.C.,Cherezov, V. (登録日: 2016-11-05, 公開日: 2017-07-26, 最終更新日: 2023-10-04)

• 主引用文献: Ishchenko, A.,Wacker, D.,Kapoor, M.,Zhang, A.,Han, G.W.,Basu, S.,Patel, N.,Messerschmidt, M.,Weierstall, U.,Liu, W.,Katritch, V.,Roth, B.L.,Stevens, R.C.,Cherezov, V.; Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody.; Proc. Natl. Acad. Sci. U.S.A., 114:8223-8228, 2017; PubMed: 28716900; DOI: 10.1073/pnas.1700891114

実験手法

X-RAY DIFFRACTION (3 Å)