5TT8
Crystal structure of the complex of Helicobacter pylori alpha-carbonic anhydrase with benzolamide
Summary for 5TT8
| Entry DOI | 10.2210/pdb5tt8/pdb |
| Related | 5TT3 5TUO 5TV3 |
| Descriptor | Alpha-carbonic anhydrase, ZINC ION, CHLORIDE ION, ... (6 entities in total) |
| Functional Keywords | alpha-carbonic anhydrase, helicobacter pylori, zinc metalloenzyme, lyase |
| Biological source | Helicobacter pylori (strain ATCC 700392 / 26695) |
| Total number of polymer chains | 8 |
| Total formula weight | 219012.53 |
| Authors | Modak, J.K.,Roujeinikova, A. (deposition date: 2016-11-02, release date: 2017-09-13, Last modification date: 2023-10-04) |
| Primary citation | Modak, J.K.,Liu, Y.C.,Supuran, C.T.,Roujeinikova, A. Structure-Activity Relationship for Sulfonamide Inhibition of Helicobacter pylori alpha-Carbonic Anhydrase. J. Med. Chem., 59:11098-11109, 2016 Cited by PubMed: 28002963DOI: 10.1021/acs.jmedchem.6b01333 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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