5TQY
CryoEM reconstruction of human IKK1, closed conformation 3
Summary for 5TQY
Entry DOI | 10.2210/pdb5tqy/pdb |
Related | 5TQW 5TQX |
EMDB information | 8436 8437 8438 8439 |
Descriptor | Inhibitor of nuclear factor kappa-B kinase subunit alpha (1 entity in total) |
Functional Keywords | kinase, conserved helix-loop-helix, transcription, oncogene, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 150293.89 |
Authors | Lyumkis, D.,Ghosh, G.,Polley, S.,Biswath, T.,Huang, D.,Passos, D.O. (deposition date: 2016-10-24, release date: 2016-11-09, Last modification date: 2024-03-13) |
Primary citation | Polley, S.,Passos, D.O.,Huang, D.B.,Mulero, M.C.,Mazumder, A.,Biswas, T.,Verma, I.M.,Lyumkis, D.,Ghosh, G. Structural Basis for the Activation of IKK1/ alpha. Cell Rep, 17:1907-1914, 2016 Cited by PubMed: 27851956DOI: 10.1016/j.celrep.2016.10.067 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (5.2 Å) |
Structure validation
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