5TPX
Bromodomain from Plasmodium Faciparum Gcn5, complexed with compound
Summary for 5TPX
Entry DOI | 10.2210/pdb5tpx/pdb |
Related | 4QNS |
Descriptor | Histone acetyltransferase GCN5, CHLORIDE ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | bromodomain, transferase, structural genomics consortium (sgc) |
Biological source | Plasmodium falciparum (isolate 3D7) |
Total number of polymer chains | 1 |
Total formula weight | 15449.90 |
Authors | Lin, Y.H.,Hou, C.F.D.,MOUSTAKIM, M.,DIXON, D.J.,Loppnau, P.,Tempel, W.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Hui, R.,BRENNAN, P.E.,Walker, J.R.,Structural Genomics Consortium (SGC) (deposition date: 2016-10-21, release date: 2017-01-04, Last modification date: 2023-10-04) |
Primary citation | Moustakim, M.,Clark, P.G.,Trulli, L.,Fuentes de Arriba, A.L.,Ehebauer, M.T.,Chaikuad, A.,Murphy, E.J.,Mendez-Johnson, J.,Daniels, D.,Hou, C.D.,Lin, Y.H.,Walker, J.R.,Hui, R.,Yang, H.,Dorrell, L.,Rogers, C.M.,Monteiro, O.P.,Fedorov, O.,Huber, K.V.,Knapp, S.,Heer, J.,Dixon, D.J.,Brennan, P.E. Discovery of a PCAF Bromodomain Chemical Probe. Angew. Chem. Int. Ed. Engl., 56:827-831, 2017 Cited by PubMed: 27966810DOI: 10.1002/anie.201610816 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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