5TP0
Human mesotrypsin in complex with diminazene
Summary for 5TP0
Entry DOI | 10.2210/pdb5tp0/pdb |
Descriptor | Trypsin-3, CALCIUM ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | trypsin, serine-type endopeptidase, serine hydrolase, complex with small molecule drug, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 24979.10 |
Authors | Kayode, O.,Soares, A.,Radisky, E.S. (deposition date: 2016-10-19, release date: 2017-05-17, Last modification date: 2023-10-04) |
Primary citation | Kayode, O.,Huang, Z.,Soares, A.S.,Caulfield, T.R.,Dong, Z.,Bode, A.M.,Radisky, E.S. Small molecule inhibitors of mesotrypsin from a structure-based docking screen. PLoS ONE, 12:e0176694-e0176694, 2017 Cited by PubMed: 28463992DOI: 10.1371/journal.pone.0176694 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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