5TO5
Structure of the TPR oligomerization domain
Summary for 5TO5
Entry DOI | 10.2210/pdb5to5/pdb |
Related | 5TO6 5TO7 |
Descriptor | Nucleoprotein TPR (2 entities in total) |
Functional Keywords | tpr oligomerization domain, receptor tyrosine kinase, met, oncogenic fusion kinases, cell cycle |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 33495.84 |
Authors | Pal, K.,Xu, Q.,Zhou, X.E.,Melcher, K.,Xu, H.E. (deposition date: 2016-10-16, release date: 2017-10-18, Last modification date: 2024-03-06) |
Primary citation | Pal, K.,Bandyopadhyay, A.,Zhou, X.E.,Xu, Q.,Marciano, D.P.,Brunzelle, J.S.,Yerrum, S.,Griffin, P.R.,Vande Woude, G.,Melcher, K.,Xu, H.E. Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases. Structure, 25:867-877.e3, 2017 Cited by PubMed: 28528776DOI: 10.1016/j.str.2017.04.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report