5TNE

Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted cis-Stilbene Oxide hydrolysis intermediate

Summary for 5TNE

Entry DOI	10.2210/pdb5tne/pdb
Related	3KD2 4DMC 5TND 5TNF 5TNG 5TNH 5TNI 5TNJ 5TNK 5TNL 5TNM 5TNN 5TNP 5TNQ 5TNR 5TNS
Descriptor	CFTR inhibitory factor, (1R,2R)-1,2-diphenylethane-1,2-diol (3 entities in total)
Functional Keywords	epoxide hydrolase, hydroxyalkyl-enzyme intermediate, hydrolase
Biological source	Pseudomonas aeruginosa (strain UCBPP-PA14)
Total number of polymer chains	4
Total formula weight	137083.38
Authors	Hvorecny, K.L.,Madden, D.R. (deposition date: 2016-10-14, release date: 2017-10-11, Last modification date: 2023-10-04)
Primary citation	Hvorecny, K.L.,Bahl, C.D.,Kitamura, S.,Lee, K.S.S.,Hammock, B.D.,Morisseau, C.,Madden, D.R. Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase. Structure, 25:697-707.e4, 2017 Cited by PubMed: 28392259 DOI: 10.1016/j.str.2017.03.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation