5TNE
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted cis-Stilbene Oxide hydrolysis intermediate
Summary for 5TNE
Entry DOI | 10.2210/pdb5tne/pdb |
Related | 3KD2 4DMC 5TND 5TNF 5TNG 5TNH 5TNI 5TNJ 5TNK 5TNL 5TNM 5TNN 5TNP 5TNQ 5TNR 5TNS |
Descriptor | CFTR inhibitory factor, (1R,2R)-1,2-diphenylethane-1,2-diol (3 entities in total) |
Functional Keywords | epoxide hydrolase, hydroxyalkyl-enzyme intermediate, hydrolase |
Biological source | Pseudomonas aeruginosa (strain UCBPP-PA14) |
Total number of polymer chains | 4 |
Total formula weight | 137083.38 |
Authors | Hvorecny, K.L.,Madden, D.R. (deposition date: 2016-10-14, release date: 2017-10-11, Last modification date: 2023-10-04) |
Primary citation | Hvorecny, K.L.,Bahl, C.D.,Kitamura, S.,Lee, K.S.S.,Hammock, B.D.,Morisseau, C.,Madden, D.R. Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase. Structure, 25:697-707.e4, 2017 Cited by PubMed: 28392259DOI: 10.1016/j.str.2017.03.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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