5TJO

Crystal structure of GTB + B trisaccharide (mercury derivative)

5TJO の概要

• エントリーDOI: 10.2210/pdb5tjo/pdb
• 関連するPDBエントリー: 5TJK 5TJL 5TJM 5TJN 5TJP
• 分子名称: Histo-blood group ABO system transferase, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]octyl beta-D-galactopyranoside, MERCURY (II) ION, ... (4 entities in total)
• 機能のキーワード: glycosyltransferases, histo blood group enzymes, product trisaccharide, gt-a fold, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36331.03

構造登録者

Legg, M.S.G.,Gagnon, S.M.L.,Evans, S.V. (登録日: 2016-10-04, 公開日: 2017-06-14, 最終更新日: 2023-10-04)

• 主引用文献: Gagnon, S.M.L.,Legg, M.S.G.,Sindhuwinata, N.,Letts, J.A.,Johal, A.R.,Schuman, B.,Borisova, S.N.,Palcic, M.M.,Peters, T.,Evans, S.V.; High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release.; Glycobiology, 27:966-977, 2017; PubMed: 28575295; DOI: 10.1093/glycob/cwx053

実験手法

X-RAY DIFFRACTION (1.57 Å)