5TIB

Gasdermin-B C-terminal domain containing the polymorphism residues Arg299:Ser306 fused to maltose binding protein

Summary for 5TIB

Entry DOI	10.2210/pdb5tib/pdb
Related PRD ID	PRD_900001
Descriptor	Sugar ABC transporter substrate-binding protein,Gasdermin-B, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ACETATE ION, ... (5 entities in total)
Functional Keywords	alpha helices, fusion protein, c-terminal domain, 2 snps, lipid binding protein
Biological source	Escherichia coli, Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	122939.12
Authors	Chao, K.,Herzberg, O. (deposition date: 2016-10-01, release date: 2017-02-01, Last modification date: 2023-10-04)
Primary citation	Chao, L.K.,Kulakova, L.,Herzberg, O. Human Gasdermin-B and disease: Sulfatide Binding, Caspase cleavage, and Structural impact of Asthma- and IBS-Associated Polymorphism Proc.Natl.Acad.Sci.Usa, 2017 Cited by DOI: 10.1073/pnas.1616783114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation