5TIB

Gasdermin-B C-terminal domain containing the polymorphism residues Arg299:Ser306 fused to maltose binding protein

5TIB の概要

• エントリーDOI: 10.2210/pdb5tib/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900001
• 分子名称: Sugar ABC transporter substrate-binding protein,Gasdermin-B, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ACETATE ION, ... (5 entities in total)
• 機能のキーワード: alpha helices, fusion protein, c-terminal domain, 2 snps, lipid binding protein
• 由来する生物種: Escherichia coli, Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 122939.12

構造登録者

Chao, K.,Herzberg, O. (登録日: 2016-10-01, 公開日: 2017-02-01, 最終更新日: 2023-10-04)

• 主引用文献: Chao, L.K.,Kulakova, L.,Herzberg, O.; Human Gasdermin-B and disease: Sulfatide Binding, Caspase cleavage, and Structural impact of Asthma- and IBS-Associated Polymorphism; Proc.Natl.Acad.Sci.Usa, 2017; DOI: 10.1073/pnas.1616783114

実験手法

X-RAY DIFFRACTION (2.6 Å)