5TI0
Crystal Structure of 2-Hydroxycyclohepta-2,4,6-triene-1-thione bound to human carbonic anhydrase 2 L198G
Summary for 5TI0
Entry DOI | 10.2210/pdb5ti0/pdb |
Related | 5TH4 5THI 5THJ 5THN |
Descriptor | Carbonic anhydrase 2, ZINC ION, 2-hydroxycyclohepta-2,4,6-triene-1-thione, ... (5 entities in total) |
Functional Keywords | carbonic anhydrase 2, complex, metalloenzyme inhibitor, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 29592.82 |
Authors | |
Primary citation | Dick, B.L.,Patel, A.,McCammon, J.A.,Cohen, S.M. Effect of donor atom identity on metal-binding pharmacophore coordination. J. Biol. Inorg. Chem., 22:605-613, 2017 Cited by PubMed: 28389830DOI: 10.1007/s00775-017-1454-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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