5THH
Crystal structure of a human tyrosyl-tRNA synthetase mutant
Summary for 5THH
Entry DOI | 10.2210/pdb5thh/pdb |
Related | 5THL |
Descriptor | Tyrosine--tRNA ligase, cytoplasmic, TYROSINE (3 entities in total) |
Functional Keywords | tyrosyl-trna synthetase, cmt mutant, ligase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P54577 |
Total number of polymer chains | 1 |
Total formula weight | 38573.66 |
Authors | Blocquel, D.,Yang, X.L. (deposition date: 2016-09-29, release date: 2017-05-17, Last modification date: 2023-10-04) |
Primary citation | Blocquel, D.,Li, S.,Wei, N.,Daub, H.,Sajish, M.,Erfurth, M.L.,Kooi, G.,Zhou, J.,Bai, G.,Schimmel, P.,Jordanova, A.,Yang, X.L. Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy. Nucleic Acids Res., 45:8091-8104, 2017 Cited by PubMed: 28531329DOI: 10.1093/nar/gkx455 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.959 Å) |
Structure validation
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