5TH4
Crystal Structure of 1-hydroxypyridine-2(1H)-thione bound to human carbonic anhydrase 2 L198G
Summary for 5TH4
Entry DOI | 10.2210/pdb5th4/pdb |
Related | 5THI 5THJ 5THN 5TI0 |
Descriptor | Carbonic anhydrase 2, ZINC ION, 1-hydroxy-2-sulfanylpyridinium, ... (6 entities in total) |
Functional Keywords | inhibitor, carbonic anhydrase 2, complex, metalloenzyme inhibitor, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 29596.76 |
Authors | |
Primary citation | Dick, B.L.,Patel, A.,McCammon, J.A.,Cohen, S.M. Effect of donor atom identity on metal-binding pharmacophore coordination. J. Biol. Inorg. Chem., 22:605-613, 2017 Cited by PubMed: 28389830DOI: 10.1007/s00775-017-1454-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.47 Å) |
Structure validation
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