5TGL

A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX

Summary for 5TGL

Entry DOI	10.2210/pdb5tgl/pdb
Descriptor	LIPASE, N-HEXYLPHOSPHONATE ETHYL ESTER (2 entities in total)
Functional Keywords	hydrolase(carboxylic esterase)
Biological source	Rhizomucor miehei (Mucor miehei)
Total number of polymer chains	1
Total formula weight	29718.16
Authors	Brzozowski, A.M.,Derewenda, U.,Derewenda, Z.S.,Dodson, G.G.,Lawson, D.,Turkenburg, J.P.,Bjorkling, F.,Huge-Jensen, B.,Patkar, S.R.,Thim, L. (deposition date: 1991-10-30, release date: 1994-01-31, Last modification date: 2024-03-06)
Primary citation	Brzozowski, A.M.,Derewenda, U.,Derewenda, Z.S.,Dodson, G.G.,Lawson, D.M.,Turkenburg, J.P.,Bjorkling, F.,Huge-Jensen, B.,Patkar, S.A.,Thim, L. A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex. Nature, 351:491-494, 1991 Cited by PubMed: 2046751 DOI: 10.1038/351491a0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation