5TEK

Apo Structure of 4-Hydroxy-tetrahydrodipicolinate Reductase from Mycobacterium tuberculosis

Summary for 5TEK

Entry DOI	10.2210/pdb5tek/pdb
Descriptor	4-hydroxy-tetrahydrodipicolinate reductase, CHLORIDE ION, SODIUM ION, ... (5 entities in total)
Functional Keywords	oxidoreductase, lysine biosynthesis
Biological source	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Cellular location	Cytoplasm : A5U6C6
Total number of polymer chains	2
Total formula weight	52900.28
Authors	Mank, N.,Pote, S.,Arnette, K.,Klapper, V.,Chruszcz, M. (deposition date: 2016-09-21, release date: 2017-10-18, Last modification date: 2023-10-04)
Primary citation	Pote, S.,Kachhap, S.,Mank, N.J.,Daneshian, L.,Klapper, V.,Pye, S.,Arnette, A.K.,Shimizu, L.S.,Borowski, T.,Chruszcz, M. Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus. Biochim Biophys Acta Gen Subj, 1865:129750-129750, 2021 Cited by PubMed: 32980502 DOI: 10.1016/j.bbagen.2020.129750 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.01 Å)

Structure validation